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最新の10件

2009-11-24

2009-10-24

2009-08-31

2009-08-27

2009-08-17

2009-08-12

2009-08-11

研究業績

2006-

  1. "Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase"
    Nakanishi K, Bonnefond L, Kimura S, Suzuki T, Ishitani R, Nureki O,
    Nature, 461 1144-8 (2009).
    PubMed: link, PDB: 3A2K 3HJ7
  2. "Structure of a tRNA-dependent kinase essential for selenocysteine decoding"
    Araiso Y, Sherrer RL, Ishitani R, Ho JM, Söll D, Nureki O,
    Proc Natl Acad Sci U S A, 106 16215-20 (2009).
    PubMed: link, PDB: 3A4N
  3. "Mg2+-dependent gating of bacterial MgtE channel underlies Mg2+ homeostasis"
    Hattori M, Iwase N, Furuya N, Tanaka Y, Tsukazaki T, Ishitani R, Maguire ME, Ito K, Maturana A, Nureki O,
    EMBO J, 28 3602-3612 (2009).
    PubMed: link, PDB: 2ZY9
  4. "Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme."
    Toh Y, Takeshita D, Numata T, Fukai S, Nureki O, Tomita K.,
    EMBO J., 28 3353-65 (2009).
    PubMed: link, PDB: 3H37 3H38 3H39 3H3A
  5. "Structural Basis of Novel Interactions Between the Small-GTPase and GDI-like Domains in Prokaryotic FeoB Iron Transporter."
    Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O.,
    Structure., 17 1345-55 (2009).
    PubMed: link, PDB: 3A1S 3A1T 3A1U 3A1V 3A1W
  6. "Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2."
    Umitsu M, Nishimasu H, Noma A, Suzuki T, Ishitani R, Nureki O.,
    Proc Natl Acad Sci U S A., 106 15616-21 (2009).
    PubMed: link, PDB: 3A27 3A26 3A25
  7. "Crystallization and preliminary X-ray diffraction analysis of the truncated cytosolic domain of the iron transporter FeoB."
    Jin Y, Hattori M, Nisimasu H, Ishitani R, Nureki O.,
    Acta Crystallogr Sect F Struct Biol Cryst Commun., 65(Pt 8) 784-7 (2009).
    PubMed: link
  8. "Structural modelling of the complex of leucyl-tRNA synthetase and mis-aminoacylated tRNA(Leu)."
    Hagiwara Y, Nureki O, Tateno M.,
    FEBS Lett., [Epub ahead of print] (2009).
    PubMed: link
  9. "The structure of alanyl-tRNA synthetase with editing domain."
    Sokabe M, Ose T, Nakamura A, Tokunaga K, Nureki O, Yao M, Tanaka I.,
    Proc Natl Acad Sci U S A , 106 11028-11033 (2009).
    PubMed: link
  10. "Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases."
    Shirakawa R, Fukai S, Kawato M, Higashi T, Kondo H, Ikeda T, Nakayama E, Okawa K, Nureki O, Kimura T, Kita T, Horiuchi H.,
    J Biol Chem. , 284 21580-8 (2009).
    PubMed: link
  11. "Identification of the nucleophilic factors and the productive complex for the editing reaction by leucyl-tRNA synthetase."
    Hagiwara Y, Nureki O, Tateno M.,
    FEBS Lett, 583(12) 1901-8 (2009).
    PubMed: link
  12. "Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon."
    Osawa T, Ito K, Inanaga H, Nureki O, Tomita K, Numata T.,
    Structure, 17(5) 713-24. (2009).
    PubMed: link
  13. "Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein."
    Higuchi T, Hattori M, Tanaka Y, Ishitani R, Nureki O.,
    Proteins, 76(3) 768-71 (2009).
    PubMed: link, PDB: 2ZZT
  14. "Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase."
    Nishimasu H, Ishitani R, Yamashita K, Iwashita C, Hirata A, Hori H, Nureki O,
    Proc Natl Acad Sci U S A, 106(20) 8180-5 (2009).
    PubMed: link, PDB: 3G5Q 3G5R 3G5S
  15. "Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4."
    Suzuki Y, Noma A, Suzuki T, Ishitani R, Nureki O,
    Nucleic Acids Res., 37(9) 2910-25 (2009).
    PubMed: link, PDB: 2ZW9 2ZWA 2ZZK
  16. "Pyrrolysyl-tRNA synthetase tRNAPyl structure reveals the molecular basis of orthogonality."
    Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Soll D and Nureki O,
    Nature, 457(7233) 1163-1167 (2009).
    PubMed: link, PDB: 2ZNI 2ZNJ
  17. "Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator."
    Seto A, Ikushima H, Suzuki T, Sato Y, Fukai S, Yuki K, Miyazawa K, Miyazono K, Ishitani R and Nureki O,
    Acta Crystallogr Sect. F Struct. Biol. Cryst. Commun., 65(Pt 1) 21-24 (2009).
    PubMed: link
  18. "Conformational transition of Sec machinery inferred from bacterial SecYE structures."
    Tsukazaki T, Mori H, Fukai S, Ishitani R, Mori T, Dohmae N, Perederina A, Sugita Y, Vassylyev D, Ito K and Nureki O,
    Nature, 455 988-991 (2008).
    PubMed: link, PDB: 2ZJS 2ZQP
  19. "Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study."
    Ishitani R, Sugita Y, Dohmae N, Furuya N, Hattori M and Nureki O.,
    Proc Natl Acad Sci U S A, 105(40) 15393-15398 (2008).
    PubMed: link
  20. "Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains."
    Sato Y, Yoshikawa A, Yamagata A, Mimura H, Yamashita M, Ookata K, Nureki O, Iwai K, Komada M and Fukai S.,
    Nature, 455 358-362 (2008).
    PubMed: link, PDB: 2ZNV 2ZNR
  21. "Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme."
    Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O and Tomita K.,
    EMBO J., 27 1944-1952 (2008).
    PubMed: link, PDB: 2ZH1 2ZH2 2ZH3 2ZH4 2ZH5 2ZH6 2ZH7 2ZH8 2ZH9 2ZHA 2ZHB
  22. "Structure, dynamics, and function of RNA modification enzymes."
    Ishitani R, Yokoyama S and Nureki O.,
    Curr Opin Struct Biol., 18(3) 330-339. (2008).
    PubMed: link
  23. "Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets."
    Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T and Horiuchi H.,
    J Biol Chem., 283(13) 8746-8755. (2008).
    PubMed: link
  24. "Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway."
    Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Okawa K, Fukai S, Nureki O, Kita T and Horiuchi H.,
    J. Biol. Chem., 283(1) 166-174 (2008).
    PubMed: link
  25. "Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation."
    Araiso Y, Palioura S, Ishitani R, Sherrer RL, O'Donoghue P, Yuan J, Oshikane H, Domae N, Defranco J, Soll D and Nureki O.,
    Nucleic Acids Res., 36(4) 1187-1199. (2008).
    PubMed: link, PDB: 2Z67
  26. "Use of layer silicate for protein crystallization: Effects of Micromica and chlorite powders in hanging drops."
    Takehara M, Ino K, Takakusagi Y, Oshikane H, Nureki O, Ebina T, Mizukami F and Sakaguchi K.,
    Anal. Biochem., 373(2) 322-329 (2008).
    PubMed: link
  27. "Animated crystallography of genetic code translation."
    Tomita K, Numata T, Fukai S, Ishitani R and Nureki O.,
    Nucleic Acids Symp. Ser. (Oxf), 51 101-102 (2007).
    PubMed: link
  28. "Crystal structure of human DAAM1 formin homology 2 domain."
    Yamashita M, Higashi T, Suetsugu S, Sato Y, Ikeda T, Shirakawa R, Kita T, Takenawa T, Horiuchi H, Fukai S and Nureki O.,
    Genes Cells., 12(11) 1255-65 (2007).
    PubMed: link, PDB: 2Z6E
  29. "Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of a cation diffusion facilitator family protein."
    Hattori M, Tanaka Y, Ishitani R and Nureki O.,
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 63(Pt 9) 771-773 (2007).
    PubMed: link
  30. "Anticodon recognition and discrimination by the alpha-helix cage domain of class I lysyl-tRNA synthetase."
    Levengood JD, Roy H, Ishitani R, Söll D, Nureki O and Ibba M.,
    Biochemistry., 46(39) 11033-11038 (2007).
    PubMed: link
  31. "Crystal Structure of the Radical SAM Enzyme Catalyzing Tricyclic Modified Base Formation in tRNA."
    Suzuki Y, Noma A, Suzuki T, Senda M, Senda T, Ishitani R and Nureki O.,
    J. Mol. Biol., 372(5) 1204-1214 (2007).
    PubMed: link, PDB: 2Z2U
  32. "Crystal structure of the MgtE Mg2+ transporter."
    Hattori M, Tanaka Y, Fukai S, Ishitani R and Nureki O.,
    Nature, 448 1072-1075 (2007).
    PubMed: link, PDB: 2YVX 2YVY 2YVZ
  33. "Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE."
    Hattori M, Tanaka Y, Fukai S, Ishitani R and Nureki O.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun. , 63(Pt 8) 682-684 (2007).
    PubMed: link
  34. "Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of the Mg2+ transporter MgtE."
    Tanaka Y, Hattori M, Fukai S, Ishitania R and Nureki O.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun, 63(Pt 8) 678-681 (2007).
    PubMed: link
  35. "Crystal structure of the Sec4p·Sec2p complex in the nucleotide exchanging intermediate state "
    Sato Y, Fukai S, Ishitani R and Nureki O,
    PNAS, 104 (19) 8305-8310 (2007).
    PubMed: link, PDB: 2EQB
  36. "Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity."
    Sato Y, Shirakawa R, Horiuchi H, Dohmae N, Fukai S and Nureki O,
    Structure, 15 245-252 (2007).
    PubMed: link, PDB: 2E7S
  37. "Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog."
    Suto K, Shimizu Y, Watanabe K, Ueda T, Fukai S, Nureki O and Tomita K.,
    EMBO J., 24 5942-5950 (2006).
    PubMed: link, PDB: 2DPT 2DPS
  38. "Complete crystallographic analysis of the dynamics of CCA sequence addition."
    Tomita K, Ishitani R, Fukai S and Nureki O.,
    Nature, 7114 956-960 (2006).
    PubMed: link, PDB: 2DVI 2DRB 2DRA 2DR9 2DR8 2DR7 2DR5
  39. "Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei."
    Yanagisawa T, Ishii R, Fukunaga R, Nureki O and Yokoyama S.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun., Pt 10 1031-1033 (2006).
    PubMed: link
  40. "Functional categorization of the conserved basic amino acid residues in TrmH [tRNA (Gm18) methyltansferase] enzymes."
    Watanabe K, Nureki O, Fukai S, Endo Y and Hori H,
    J. Biol. Chem., 45 34630-34639 (2006).
    PubMed: link
  41. "Structural basis of RNA-dependent recruitment of glutamine to the genetic code"
    Oshikane H, Sheppard K, Fukai S, Nakamura Y, Ishitani R, Numata T, Sherrer RL, Feng L, Schmitt E, Panvert M, Blanquet S, Mechulam Y, Soll D and Nureki O.,
    Science, 312 1950-1954 (2006).
    PubMed: link, PDB: 2D6F
  42. "Snapshots of tRNA sulphuration via an adenylated intermediate"
    Numata T, Ikeuchi Y, Fukai S, Suzuki T and Nureki O.,
    Nature, 442 419-424 (2006).
    PubMed: link, PDB: 2DEU 2DET 2DER
  43. "Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus"
    Tsukazaki T, Mori H, Fukai S, Numata T, Perederina A, Adachi H, Matsumura H, Takano K, Murakami S, Inoue T, Mori Y, Sasaki T, Vassylyev DG, Nureki O and Ito K.,
    Acta Crystallographica, F., 62 376-380 (2006).
    PubMed: link
  44. "Crystallization and preliminary X-ray analysis of tRNA thiolation enzyme MnmA from Escherichia Coli complexed with tRNAGlu"
    Numata T, Ikeuchi Y, Fukai S, Adachi H, Matsumura H, Takano K, Murakami S, Inoue T, Mori Y, Sasaki T, Suzuki T and Nureki O.,
    Acta Crystallographica F., 62 368-371 (2006).
    PubMed: link
  45. "Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa"
    Sengoku T, Nureki O, Nakamura A, Kobayashi S and Yokoyama S.,
    Cell, 125 287-300 (2006).
    PubMed: link, PDB: 2DB3
  46. "Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex"
    Numata T, Fukai S, Ikeuchi Y, Suzuki T and Nureki O.,
    Structure, 14 357-366 (2006).
    PubMed: link, PDB: 2D1P


2001-2005

  1. "Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues."
    Watanabe K, Nureki O, Fukai S, Endo Y, Hori H.,
    Nucleic Acids Symp Ser (Oxf)., 49 301-302 (2005).
    PubMed: link
  2. "Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii"
    Fukunaga R, Ishitani R, Nureki O, Yokoyama S.,
    Acta Crystallographica F., 61 30-32 (2005).
    PubMed: link
  3. "Structural basis for anticodon recognition by methionyl-tRNA synthetase"
    Nakanishi K, Ogiso Y, Nakama T, Fukai S, Nureki O.,
    Nat. Struct. Mol. Biol., 12 931-932 (2005).
    PubMed: link
  4. "Recent progress of structural biology of tRNA processing and modification"
    Nakanishi K, Nureki O.,
    Mol. Cells, 19 157-166 (2005).
    PubMed: link
  5. "Structural basis for lysidine formation by ATP pyrophosphatase accompanied with a lysine-specific loop and a tRNA-recognition domain"
    Nakanishi K, Fukai S, Ikeuchi Y, Soma A, Sekine Y, Suzuki T, Nureki O.,
    Proc. Natl. Acad.Sci. USA, 21 7487-7492 (2005).
    PubMed: link, PDB: 1WY5
  6. "Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family"
    Watanabe K, Nureki O, Fukai S, Ishii R, Okamoto H, Yokoyama S, Endo Y, Hori H.,
    J. Biol. Chem., 280 10368-10377 (2005).
    PubMed: link
  7. "Structural basis for template-independent RNA polymerization"
    Tomita K, Fukai S, Ishitani R, Ueda T, Takeuchi N, Vassylyev DG, Nureki O.,
    Nature, 430 700-704 (2004).
    PubMed: link, PDB: 1VFG
  8. "Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme"
    Nureki O, Watanabe K, Fukai S, Ishii R, Endo Y, Hori H, Yokoyama S.,
    Structure, 12 593-602 (2004).
    PubMed: link, PDB: 1V2X
  9. "Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue."
    Sengoku T, Nureki O, Dohmae N, Nakamura A, Yokoyama S.,
    Acta Crystallogr D., 60 320-322 (2004).
    PubMed: link, PDB: 2DB3
  10. "Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl- tRNA synthetase and its complex with L-valine"
    Fukunaga R, Fukai S, Ishitani R, Nureki O, Yokoyama S.,
    J. Biol. Chem., 279 8396-8402 (2004).
    PubMed: link, PDB: 1UE0 1UDZ
  11. "Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein."
    Fujikawa N, Kurumizaka H, Nureki O, Tanaka Y, Yamazoe M, Hiraga S, Yokoyama S.,
    Nucleic Acids Res., 02;32 82-92 (2004).
    PubMed: link, PDB: 1J3E 1IU3
  12. "A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase."
    Kise Y, Lee SW, Park SG, Fukai S, Sengoku T, Ishii R, Yokoyama S, Kim S, Nureki O.,
    Nat. Struct. Mol. Biol., 11 149-156 (2004).
    PubMed: link, PDB: 1ULH
  13. "The Activation Mechanism of the Epidermal Growth Factor Receptor"
    Saito K, Ogiso H, Ishitani R, Nureki O, Fukai S, Yamanaka M, Kim J H, Shirouzu M, Yokoyama S,
    The Japnese Peptide Society, 93-96 (2003).
  14. "The Crystal Structure of a Putative Aspartate Aminotransferase Belonging to Subgroup IV"
    Katsura Y, Shirouzu M, Yamaguchi H, Ishitani R, Nureki O, Kuramitsu S, Hayashi H, Yokoyama S.,
    Proteins, 55 487-492 (2003).
    PubMed: link
  15. "Crystal structure of the human CENP-B dimerization domain at 1.65 A resolution."
    Tawaramoto MS, Park SY, Tanaka Y, Nureki O, Kurumizaka H, Yokoyama S.,
    J. Biol. Chem., 278 51454-51461 (2003).
    PubMed: link, PDB: 1UFI
  16. "Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis"
    Ito N, Nureki O, Shirouzu M, Yokoyama S, Hanaoka F.,
    Genes Cells, 8 913-923 (2003).
    PubMed: link, PDB: 1V34 1V33
  17. "Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure."
    Okabe M, Tomita K, Ishitani R, Ishii R, Takeuchi N, Arisaka F, Nureki O, Yokoyama S.,
    EMBO J., 22 5918-5927 (2003).
    PubMed: link, PDB: 1UEV 1UEU 1UET
  18. "Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I and class II lysyl-tRNA synthetases."
    Polycarpo C, Ambrogelly A, Ruan B, Tumbula-Hansen D, Ataide SF, Ishitani R, Yokoyama S, Nureki O, Ibba M, Soll D.,
    Mol. Cell, 12 287-294 (2003).
    PubMed: link
  19. "Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus."
    Ishii R, Nureki O, Yokoyama S.,
    J. Biol. Chem., 278 32397-32404 (2003).
    PubMed: link, PDB: 1UDS 1UDQ 1UDO 1UDN
  20. "Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic-code expansion"
    Kobayashi T, Nureki O, Ishitani R, Yaremchuk A, Tukalo M, Cusack S, Sakamoto K, Yokoyama S.,
    Nat. Struct. Biol., 10 425-432 (2003).
    PubMed: link, PDB: 1J1U
  21. "Structural basis of the replication origin recognition by the DnaA protein"
    Fujikawa N, Kurumizaka H, Nureki O, Terada T, Shirouzu M, Katayama T, Yokoyama S.,
    Nucleic Acids Res., 31 2077-2086 (2003).
    PubMed: link, PDB: 1J1V
  22. "Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme"
    Ishitani R, Nureki O, Nameki N, Okada N, Nishimura S, Yokoyama S.,
    Cell, 113 383-394 (2003).
    PubMed: link, PDB: 1J2B
  23. "ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding"
    Sekine S, Nureki O, Dubois DY, Bernier S, Chenevert R, Lapointe J, Vassylyev DG, Yokoyama S.,
    EMBO J., 22 676-688 (2003).
    PubMed: link, PDB: 1N78 1N77 1N75 1J09
  24. "Mechanism of molecular interactions for tRNAVal recognition by valyl-tRNA synthetase"
    Fukai S, Nureki O, Sekine S, Shimada A, Vassylyev DG, Yokoyama S.,
    RNA, 8 100-111 (2003).
    PubMed: link, PDB: 1IYW 1IVS
  25. "Crystal structure of human epidermal growth factor in complex with the extracellular domains of the receptor"
    Ogiso H, Ishitani R, Nureki O, Fukai S, Yamanaka M, Kim JH, Saito K, Sakamoto A, Inoue M, Shirouzu M, Yokoyama S.,
    Cell, 110 775-787 (2002).
    PubMed: link, PDB: 1IVO
  26. "Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form."
    Kagawa W, Kurumizaka H, Ishitani R, Fukai S, Nureki O, Shibata T, Yokoyama S.,
    Mol. Cell, 10 359-371 (2002).
    PubMed: link
  27. "An enzyme with a deep trefoil knot for the active-site architecture"
    Nureki O, Shirouzu M, Hashimoto K, Ishitani R, Terada T, Tamakoshi M, Oshima T, Chijimatsu M, Takio K, Vassylyev DG, Shibata T, Inoue Y, Kuramitsu S, Yokoyama S.,
    Acta Crystallogr. D., 58 1129-1137 (2002).
    PubMed: link, PDB: 1IPA
  28. "Functional convergence of two lysyl-tRNA synthetases with unrelated topologies"
    Terada T, Nureki O, Ishitani R, Ambrogelly A, Ibba M, Soll D, Yokoyama S.,
    Nat. Struct. Biol., 9 257-262 (2002).
    PubMed: link, PDB: 1IRX
  29. "Crystal structure of archaeosine tRNA-guanine transglycosylase"
    Ishitani R, Nureki O, Fukai S, Kijimoto T, Nameki N, Watanabe M, Kondo H, Sekine M, Okada N, Nishimura S, Yokoyama S.,
    J. Mol. Biol., 318 665-677 (2002).
    PubMed: link, PDB: 1IT8 1IT7 1IQ8
  30. "Mutation Separation of two pathways for editing by a class I tRNA synthetase"
    Hendrickson TL, Nomanbhoy TK, de Crecy-Lagard V, Fukai S, Nureki O, Yokoyama S, Schimmel P.,
    Mol. Cell, 9 353-362 (2002).
    PubMed: link
  31. "DNA kink at the contact site with an arginine-rich helix of human centeromere protein B"
    Tanaka Y*, Nureki O*, Kurumizaka H*, Fukai S, Kawaguchi S, Ikuta M, Iwahara J, Okazaki T and Yokoyama S (*equal contribution),
    EMBO J, 20 6612-6618 (2001).
  32. "Structural basis for amino acid and tRNA recognition by class I aminoacyl-tRNA synthetases."
    Nureki O, Fukai S, Sekine S, Shimada A, Terada T, Nakama T, Shirouzu M, Vassylyev DG, Yokoyama S,
    Cold Spring Harb Symp Quant Biol., 66 167-173 (2001).
    PubMed: link
  33. "Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA."
    Tanaka Y, Nureki O, Kurumizaka H, Fukai S, Kawaguchi S, Ikuta M, Iwahara J, Okazaki T, Yokoyama S.,
    EMBO J., 20 6612-6618 (2001).
    PubMed: link, PDB: 1HLV
  34. "Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase"
    Nakama T, Nureki O, Yokoyama S.,
    J. Biol. Chem., 276 47387-47393 (2001).
    PubMed: link, PDB: 1JZS 1JZQ
  35. "Structural and mutational studies of the recognition of the arginine tRNA-specific major identity element, A20, by arginyl-tRNA synthetase"
    Shimada A, Nureki O, Goto M, Takahashi S, Yokoyama S.,
    Proc. Natl. Acad.Sci. USA, 98 13537-13542 (2001).
    PubMed: link, PDB: 1IQ0
  36. "Crystallization and preliminary X-ray analysis of a DNA primase from the hyperthermophilic archaeon, Pyrococcus horikoshii"
    Ito N, Nureki O, Shirouzu M, Yokoyama S, Hanaoka F.,
    J. Biochem., 130 727-730 (2001).
    PubMed: link
  37. "Selenomethionine incorporation into a protein by cell-free synthesis"
    Kigawa T, Yamaguchi-Nunokawa E, Kodama K, Matsuda T, Yabuki T, Matsuda N, Ishitani R, Nureki O, Yokoyama S.,
    J. Struc. Func. Gen., 2 87-104 (2001).
    PubMed: link
  38. "Crystallization and preliminary X-ray analysis of archaeosine tRNA-guanine transglycosylase from Pyrococcus horikoshii"
    Ishitani R, Nureki O, Kijimoto T, Watanabe M, Kondo H, Nameki N, Okada N, Nishimura S, Yokoyama S.,
    Acta Crystallogr. D., 57 1659-1662 (2001).
    PubMed: link
  39. "Crystal structure of human AUH protein, a single-stranded RNA-binding homologue of enoyl-CoA hydratase"
    Kurimoto K, Fukai S, Nureki O, Muto Y, Yokoyama S.,
    Structure, 9 1253-1263 (2001).
    PubMed: link, PDB: 1HZD
  40. "Crucial role of the HIGH-loop lysine for the catalytic activity of arginyl-tRNA synthetase"
    Sekine S, Shimada A, Nureki O, Cavarelli J, Moras D, Vassylyev DG, Yokoyama S.,
    J. Biol. Chem., 276 3723-3726 (2001).
    PubMed: link
  41. "Structural basis for anticodon recognition by discriminating glutamyl-tRNA synthetase"
    Sekine S, Nureki O, Shimada A, Vassylyev DG, Yokoyama S.,
    Nat. Struct. Biol., 8 203-206 (2001).
    PubMed: link, PDB: 1N78 1N77 1N75 1J09 1G59


1996-2000

  1. "Gene cloning, expression, crystallization, and preliminary X-ray analysis of Thermus thermophilus arginyl-tRNA synthetase"
    Shimada A, Nureki O, Dohmae N, Takio K, Yokoyama S.,
    Acta Crystallogr.D., 57 272-275 (2000).
    PubMed: link
  2. "Structural basis for double-sieve discrimination of the cognate L-valine from L-isoleucine and L-threonine by the complex of tRNAVal and valyl-tRNA synthetase"
    Fukai S, Nureki O, Sekine S, Shimada A, Tao J, Vassylyev DG, Yokoyama S.,
    Cell, 103 793-803 (2000).
    PubMed: link, PDB: 1IVS 1GAX
  3. "Crystallization and preliminary X-ray diffraction analysis of the extracellular domain of the cell surface antigen CD38 complexed with ganglioside"
    Kukimoto M, Nureki O, Shirouzu M, Katada T, Hirabayashi Y, Sugiya H, Furuyama S, Yokoyama S, Hara-Yokoyama M.,
    J. Biochem., 127 181-184 (2000).
    PubMed: link
  4. "The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules"
    Sugiura I, Nureki O, Ugaji-Yoshikawa Y, Kuwabara S, Shimada A, Tateno M, Lorber B, Giege R, Moras D, Yokoyama S, Konno M.,
    Structure, 8 197-208 (2000).
    PubMed: link
  5. "Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features"
    Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S.,
    J. Mol. Biol., 294 1287-1297 (1999).
    PubMed: link, PDB: 1QQT
  6. "Proofreading by isoleucyl-transfer RNA synthetase"
    O. Nureki, D. G. Vassylyev, M. Tateno, A. Shimada, T. Nakama, S. Fukai, M. Konno, T. L. Hendrickson, P. Schimmel, and S. Yokoyama,
    Science, 283 459 (1999).
  7. "The identity determinants required for the discrimination between tRNAGlu and tRNAAsp by glutamyl-tRNA synthetase from Escherichia coli"
    Sekine S, Nureki O, Tateno M, Yokoyama S.,
    Eur. J. Biochem., 261 354-360 (1999).
    PubMed: link
  8. "Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein"
    Handa N, Nureki O, Kurimoto K, Kim I, Sakamoto H, Shimura Y, Muto Y, Yokoyama S.,
    Nature, 398 579-585 (1999).
    PubMed: link, PDB: 1B7F
  9. "Enzyme structure with two catalytic sites for double-sieve selection of substrate"
    Nureki O, Vassylyev DG, Tateno M, Shimada A, Nakama T, Fukai S, Konno M, Hendrickson TL, Schimmel P, Yokoyama S.,
    Science, 280 578-582 (1998).
    PubMed: link, PDB: 1ILE
  10. "Major identity determinants in the "augmented D helix" of tRNAGlu from Escherichia coli"
    Sekine S, Nureki O, Sakamoto K, Niimi T, Tateno M, Go M, Kohno T, Brisson A, Lapointe J, Yokoyama S.,
    J. Mol. Biol., 256 685-700 (1996).
    PubMed: link


1991-1995

  1. "The zinc-binding site of Escherichia coli glutamyl-tRNA synthetase is located in the acceptor-binding domain"
    Liu J, Gagnon Y, Gauthier J, Furenlid L, L'Heureux PJ, Auger M, Nureki O, Yokoyama S, Lapointe J.,
    J. Biol. Chem., 270 15162-15169 (1995).
    PubMed: link
  2. "A three-dimensional structure model of the complex of glutamyl-tRNA synthetase and its cognate tRNA"
    Tateno M, Nureki O, Sekine S, Kaneda K, Go M, Yokoyama S.,
    FEBS Lett., 377 77-81 (1995).
    PubMed: link
  3. "Architectures of the class-defining and specific domains of glutamyl-tRNA synthetase"
    Nureki O, Vassylyev DG, Katayanagi K, Shimizu T, Sekine S, Kigawa T, Miyazawa T, Yokoyama S, Morikawa K.,
    Science, 267 1958-1965 (1995).
    PubMed: link, PDB: 1N78 1N77 1N75 1J09 1GLN
  4. "Recognition of the anticodon loop of tRNA1Ile by isoleucyl-tRNA synthetase from Escherichia coli"
    T. Niimi, O. Nureki, T. Yokogawa, N. Hayashi, K. Nishikawa, K. Watanabe, S. Yokoyama,
    Nucleosides and Nucleotides, 13 1231-1237 (1994).
  5. "Molecular recognition of the identity-determinant set of isoleucine transfer RNA from Escherichia coli"
    Nureki O, Niimi T, Muramatsu T, Kanno H, Kohno T, Florentz C, Giege R, Yokoyama S.,
    J. Mol. Biol., 236 710-724 (1994).
    PubMed: link
  6. "Chemical modification and mutagenesis studies on zinc binding of aminoacyl-tRNA synthetases"
    Nureki O, Kohno T, Sakamoto K, Miyazawa T, Yokoyama S.,
    J. Biol. Chem., 268 15368-15373 (1993).
    PubMed: link
  7. "Glutamyl-tRNA synthetase from Thermus thermophilus HB8"
    Nureki O, Suzuki K, Hara-Yokoyama M, Kohno T, Matsuzawa H, Ohta T, Shimizu T, Morikawa K, Miyazawa T, Yokoyama S.,
    Eur. J. Biochem., 204 465-472 (1992).
    PubMed: link
  8. "Mechanisms of molecular recognition of tRNAs by aminoacyl-tRNA synthetases."
    Nureki O, Tateno M, Niimi T, Kohno T, Muramatsu T, Kanno H, Muto Y, Giege R, Yokoyama S.,
    Nucleic Acids Symp. Ser., 25 165-166 (1991).
    PubMed: link
  9. "Methionyl-tRNA synthetase gene from an extreme thermophile, Thermus thermophilus HB8"
    Nureki O, Muramatsu T, Suzuki K, Kohda D, Matsuzawa H, Ohta T, Miyazawa T, Yokoyama S.,
    J. Biol. Chem., 266 3268-3277 (1991).
    PubMed: link


講演論文

  1. "Structural basis for amino acid and tRNA recognition by class I aminoacyl-tRNA synthetases."
    Nureki O, Fukai S, Sekine S, Shimada A, Terada T, Nakama T, Shirouzu M, Vassylyev DG, Yokoyama S.,
    Cold Spring Harbor Symposia on Quantitative Biology., LXVI 167-173 (2001).
    PubMed: link
  2. "Mechanisms of molecular recognition of tRNAs by aminoacyl-tRNA synthetases."
    Nureki O, Tateno M, Niimi T, Kohno T, Muramatsu T, Kanno H, Muto Y, Giege R, Yokoyama S.,
    Nucleic Acids Symp. Ser., 25 165-166 (1991).
    PubMed: link
  3. "Recognition of tRNA identity determinants by aminoacyl-tRNA synthetases."
    Muramatsu T, Nureki O, Kanno H, Niimi T, Tateno M, Kohno T, Kawai G, Miyazawa T, Muto Y, Yokoyama S.,
    Nucleic Acids Symp. Ser., 22 119-120 (1990).
    PubMed: link


書籍

  1. "Architectures of class I aminoacyl-tRNA synthetases"
    O. Nureki, and S. Yokoyama,
    Tracing Biology Evolution in Protein and Gene Structures, (Edited by M. Go and P. Schimmel) Elsevier Science, pp. 23-35 (1995).
  2. "Conformational change of tRNA upon interaction of the identity-determinant set with aminoacyl-tRNA synthetase8"
    O. Nureki, T. Niimi, Y. Muto, H. Kanno, T. Kohno, T. Muramatsu, G. Kawai, T. Miyazawa, R. Giege, C. Florentz, and S. Yokoyama,
    The Translational Apparatus, Plenum Press, New York pp.59-66 (1993).


総説・解説

  1. "[Dynamic mechanism of CCA-adding polymerization reaction]"
    Nureki O.,
    Seikagaku., 80(5) 429-34 (2008).
    PubMed: link
  2. "[Structural basis for the mechanism of Mg2 homeostasis by MgtE transporter]"
    Hattori M, Nureki O.,
    Tanpakushitsu Kakusan Koso., 53(3) 242-8. (2008).
    PubMed: link
  3. "細胞の生と死を統括するアミノアシルtRNA合成酵素複合体"
    濡木理,
    蛋白質核酸酵素, 50巻 1264-1270 (2005).
  4. "アミノアシルtRNA合成酵素"
    濡木理,
    タンパク質工学の基礎, 131-147 (2004).
  5. "タンパク質の高次構造の決定法"
    濡木理・河合剛太,
    タンパク質工学の基礎, 41-61 (2004).
  6. "tRNAプロセシング・修飾酵素の構造生物学"
    濡木理,
    細胞工学, 22巻 951-955 (2003).
  7. "転写後修飾酵素による認識のためのtRNAの新たな構造"
    石谷隆一郎・濡木理・横山茂之,
    実験医学, 8巻 1657-1660 (2003).
  8. "RNA・タンパク質相互作用"
    濡木理,
    RNAがわかる, 70-82 (2003).
  9. "アミノアシルtRNA合成酵素aaRSのtRNA認識機構"
    濡木理,
    蛋白質核酸酵素, 46巻 1651-1660 (2001).
  10. "正確な遺伝暗号の翻訳"
    濡木理,
    遺伝子産物（タンパク質）の形を観る：構造生物学とは何か, （第１３回「大学と科学」　公開シンポジウム組織委員会） 51-64 (1999).
  11. "tRNAへのアミノ酸の結合 - その起源と進化 -"
    濡木理,
    化学と工業, 50巻 181-189 (1999).
  12. "立体構造から見たグルタミルtRNA合成酵素の進化"
    濡木理・横山茂之,
    生物物理, 37巻 321-325 (1997).
  13. "トランスファーRNAの構造生物学"
    濡木理・横山茂之,
    科学, 68巻 548-555 (1996).
  14. "アミノアシルtRNA合成酵素：構造的見地から見た基質認識機構と分子進化"
    濡木理・横山茂之,
    日本結晶学会誌, 38巻 60-67 (1996).
  15. "アミノアシルtRNA合成酵素によるtRNA認識のメカニズム"
    濡木理・横山茂之,
    蛋白質核酸酵素, 40巻 1609-1619 (1995).
  16. "アミノアシルtRNA合成酵素"
    濡木理・横山茂之,
    蛋白質核酸酵素, 39巻 221-231 (1994).
  17. "tRNAの機能構造とアイデンティティー決定因子"
    濡木理・横山茂之,
    遺伝, 48巻 13-19 (1994).